Process for producing antibiotic montmorillonite powder in which ag or cu or their oxides are combin

专利摘要:
To montmorillonite particulates, metals, in particular Ag, Cu or oxides thereof, such as AgO or CuO, or to the montmorillonite particulates of Ag, Cu or AgO or CuO In any one of the methods of bonding, metal ions, in particular Ag ++ or Cu ++ aqueous solution, or Ag on the montmorillonite microparticles, Ag on the metal of Cu or montmorillonite microparticles Montmorillonite used for antimicrobial, bactericidal or antifungal agents by using any one of powder heat treatment as a method of bonding metals of Cu or oxides thereof, or copper or these Method for producing montmorillonite antimicrobial powder to which the oxide is bonded.
公开号:KR20040033529A
申请号:KR1020020062657
申请日:2002-10-15
公开日:2004-04-28
发明作者:김인달
申请人:김인달；
IPC主号:

专利说明:

Process for producing antibiotic montmorillonite powder in which Ag or Cu or their oxides are combined with montmorillonite
[4] The present invention relates to a method for producing an antimicrobial powder in which Ag, Cu or Ag compounds, and Cu compounds are respectively bonded to montmorillonite as an antibacterial, bactericidal or antifungal agent.
[5] Montmorillonite is a type of volcanic ash, for example, a type of clay mineral composed mainly of about 70% SiO ₂ , about 20% Al ₂ O ₃ , and about 10% Fe ₂ O ₃ , and the crystals are SiO ₂ type lattice It is formed and is not toxic to humans and animals at all. When the material is ground and dried after water treatment, the particles become ultra-fine particles with a particle size of 20 to 40 nanometers.The montmorillonite ultra-fine particles are combined with Ag (AgO), Cu (CuO) or Ag and AgO, Cu, and CuO properly. When it is possible to produce an antimicrobial powder that is harmless to humans and animals. Since montmorillonite has a strong basicity (minus ion), it is used as an ion exchange material.
[6] These antimicrobial powders can be widely used as cosmetic additives, paint additives, feed additives, pesticide additives and the like.
[7] Conventionally, there was no antimicrobial substance using montmorillonite using silver or copper or oxides thereof. That is, there is no example in which metal is bonded to montmorillonite microparticles.
[8] In general, bacteria or fungi that live on the floor of the building or on the skin, leaves, etc. are micron-sized and can grow and proliferate in the microcavity. In this way, it must be possible to penetrate into the microcavity and be always harmless to animals and plants.
[9] However, there are no known fungicides that can penetrate even small pores without harming the human body. In particular, since most of the fungicides are manufactured on the basis of chlorine or strongly oxidizable by the sterilization mechanism, the action time is short, and most of them are disadvantageous to humans and animals and plants.
[10] Therefore, the present invention is to make the montmorillonite particles combined with these antimicrobial substances to be less than 40 nanometers to easily penetrate into the pores of the skin pores, plant leaves, roots, etc. to exhibit a bactericidal action.
[11] In particular, since montmorillonite has a layered structure of the particles, the present invention utilizes an antimicrobial substance for a long time between layers.
[12] Accordingly, the present invention, as described above, is a combination of montmorillonite particles, metals, in particular Ag, Cu or oxides thereof, such as AgO or CuO, or montmorillonite particles. In bonding any one of the above Ag, Cu or AgO, CuO, using a metal ion, in particular Ag ⁺ , Cu ⁺⁺ aqueous solution, or a metal of the above Ag, Cu in montmorillonite particles or their The above object is solved by using an antimicrobial agent, a bactericide or an antifungal agent by using any one of the powder heat treatment method for the bonding method of the oxide.
[1] Figure 1 shows the structure of the oxidative constituents in the atmosphere as an embodiment of the present invention.
[2] <Code Description of Main Parts of Drawing>
[3] 1. Heater 2. Door door 3. Fireproof material
[13] Here, the montmorillonite is pulverized by grinding or the like to make particles. When the montmorillonite particles are mixed in distilled water at a ratio of about 1: 100 and stirred for about 10 minutes in a magnet stirrer, a montmorillonite colloidal solution is prepared, and Ag, AgO powder is added to the solution, or a water-soluble Ag compound. (AgNO _3, AgF, etc.) about 15 after preparing the aqueous solution of Ag ⁺ ion is Ag ⁺ ion concentration of 5,000ppm ~ 15,000ppm, and stirred and mixed and then the montmorillonite colloidal solution with an aqueous solution of the Ag compound by When left for more than montmorillonite reacts with Ag ⁺ to form agglomerates (precipitates), and when it is heated for 8 to 12 hours at 550 ℃ ~ 680 ℃ in an oxidizing atmosphere, mont impregnated with Ag and AgO Morillonite is prepared as a solid. The heat-treated solid is pulverized to a particle size of 20 to 40 nanometers to make the montmorillonite antimicrobial powder of the present invention.
[14] In the case of adding Cu, CuO powder instead of Ag or AgO or using a water-soluble Cu compound, montmorillonite antimicrobial powder is produced in the same manner as in the case of Ag and AgO.
[15] In this case, when heated to less than 550 ℃ in an oxidizing atmosphere, a sufficient reaction is not obtained, and when heated to over 680 ℃ to produce a peroxide compound, the antimicrobial properties are lowered, the application efficiency is lowered when used. In addition, when heating for less than 8 hours, the reaction is not sufficient, and if heated for more than 12 hours, peroxide compounds are likely to be produced.
[16] The present invention will be described in more detail by one embodiment.
[17] (Example)
[18] Example 1
[19] 10 g of montmorillonite, which was ground and ground to a particle size of 20 to 40 nanometers (nanometer), was mixed with 1000 ml of distilled water and stirred for 10 minutes with a magnetic stirrer. The montmorillonite colloidal solution prepared by stirring was stored in two 500 ml containers.
[20] Next, 500 mL of Ag + ion solution having Ag ⁺ ion concentration of 5,000 ppm to 15,000 ppm (here 10,000 ppm) was prepared using a water-soluble Ag compound (AgNo3, AgF).
[21] The solution prepared as described above was mixed and stirred for 10 minutes in a stirrer and left at room temperature for 24 hours. The heat treatment reaction formula at this time was as follows.
[22] Montmorillonite ^{(M -) + Ag + +} NO 3 + H 2 O
[23] ⇒ montmorillonite (Ag) + NO ₃ ^- + H ₂ O and and and and and (1)
[24] The aggregated particles were collected in Equation (1) to 600 ° C. × 10 hr in an oxidizing atmosphere. Heated. The reaction formula at this time is as follows.
[25] Heated montmorillonite (Ag) ⇒ montmorillonite (Ag + AgO) ... (2)
[26] Sample A was prepared by pulverizing the solid that was heat-treated in Equation (2) to a size of 20-40 nanometers in a grinder such as a grinder.
[27] Example 2
[28] 10 g of montmorillonite having a particle size of 20 to 40 nanometers was mixed with 1000 ml of distilled water and stirred in a magnetic stirrer for 10 minutes. The prepared montmorillonite colloidal solution was stored in two 500 ml containers.
[29] Next, 500 mL of Cu ⁺⁺ ion aqueous solution prepared from 5,000 ppm to 15,000 ppm (here 10,000 ppm) was prepared using a water-soluble Cu compound (CuSo ₄ , CuF _2, etc.).
[30] Then, the two solutions prepared by the above process were mixed and stirred in a stirrer for 10 minutes, and then left at room temperature for 24 hours. The reaction formula at this time was the same as that of Formula (3).
[31] Montmorillonite ^{(2M -) + Cu ++ +} So 4 - + H 2 O
[32] ⇒ montmorillonite (Cu) + SO ₄ ^- + H ₂ O and and and and and (3)
[33] Collect the aggregated particles by the above reaction 600 ℃ × 10hr in an oxidizing atmosphere. Heated. The reaction formula according to the heat treatment at this time was as follows.
[34] Heated montmorillonite (Cu) ⇒ montmorillonite (Cu + CuO)
[35] In other words, it has been found that when the solution-treated montmorillonite is heated, CuO, an oxide of Cu, is formed and bonded to montmorillonite like Cu. Thus prepared sample was ground to make Sample B.
[36] Table 1. Antimicrobial Test Results of Samples A and B
[37]
[38] In order to test the antimicrobial properties of the powder prepared as described above was applied to the E. Coli strain in an aqueous solution of 30ppm sample concentration. The initial concentration of the strain was 9 × 10 ¹⁰ . The bacterium concentration affected by the montmorillonite antimicrobial powder of the present invention was significantly reduced over time. As can be seen from the antimicrobial test results of Table 1, both samples A and B were antimicrobial, Sample A was found to be excellent in antibacterial, bactericidal, anti-fungal than Sample B.

权利要求:
Claims (2)
[1" claim-type="Currently amended] To montmorillonite particulates, metals, in particular Ag, Cu or oxides thereof, such as AgO or CuO, or to the montmorillonite particulates of Ag, Cu or AgO or CuO In bonding any of these, metal ions, in particular using Ag ⁺⁺ , Cu ₊₊ aqueous solution, or Ag on the montmorillonite particles, Ag on the metal of Cu or montmorillonite particles, Montmorillonite is used in antibacterial, bactericidal or antifungal agents by using any one of powder heat treatment methods as a method of bonding Cu metals or oxides thereof to silver or copper or these Method for producing montmorillonite antimicrobial powder to which the oxide is bonded.
[2" claim-type="Currently amended] The method of claim 1, wherein the montmorillonite is made of fine particles of 20 to 40 nanometers, mixed with distilled water and stirred to prepare a montmorillonite colloidal solution, and then Ag ⁺ ion concentration is increased using a water-soluble Ag compound. preparing 5,000ppm ~ 15,000ppm Ag ⁺ ion is an aqueous solution, mixed, stirred, and allowed to stand at room temperature, characterized in that the collected particles be aggregated by 8-12 hours heating at 550 ~ 680 ℃ in an oxidizing atmosphere is obtained by Ag and AgO compound Method for producing montmorillonite antimicrobial powder to which the oxide to be bonded.

类似技术:

---

公开号 | 公开日 | 专利标题

---

Jadalannagari et al.2014|Antimicrobial activity of hemocompatible silver doped hydroxyapatite nanoparticles synthesized by modified sol–gel technique

---

Mavani et al.2013|Synthesis of silver nanoparticles by using sodium borohydride as a reducing agent

---

US10034478B2|2018-07-31|Antimicrobial articles of manufacture

---

Amany et al.2012|Effect of reducing and protecting agents on size of silver nanoparticles and their anti-bacterial activity

---

Liu et al.2013|The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes

---

Rajiv et al.2013|Bio-Fabrication of zinc oxide nanoparticles using leaf extract of Parthenium hysterophorus L. and its size-dependent antifungal activity against plant fungal pathogens

---

Daima et al.2014|Synergistic influence of polyoxometalate surface corona towards enhancing the antibacterial performance of tyrosine-capped Ag nanoparticles

---

KR101500590B1|2015-03-09|Antimicrobial and antiviral composition comprising cuprous oxide, and method of producing the same

---

Shanmugam et al.2014|Copper substituted hydroxyapatite and fluorapatite: synthesis, characterization and antimicrobial properties

---

Ali et al.2016|Green synthesis of silver nanoparticles using apple extract and its antibacterial properties

---

US8563020B2|2013-10-22|Compositions and methods for antimicrobial metal nanoparticles

---

Yasin et al.2013|Biosynthesis of silver nanoparticles by bamboo leaves extract and their antimicrobial activity

---

US6379712B1|2002-04-30|Nanosilver-containing antibacterial and antifungal granules and methods for preparing and using the same

---

US5441717A|1995-08-15|Process for producing antimicrobial compounds

---

Iqbal et al.2014|Characterization, antibacterial and in vitro compatibility of zinc–silver doped hydroxyapatite nanoparticles prepared through microwave synthesis

---

Díaz et al.2009|Synthesis and antimicrobial activity of a silver-hydroxyapatite nanocomposite

---

EP1419119B1|2006-05-03|Water-insoluble, antimicrobial silicate glass and use thereof

---

Naseem et al.2015|Antibacterial activity of green synthesis of iron nanoparticles using Lawsonia inermis and Gardenia jasminoides leaves extract

---

EP2035567B1|2011-12-14|Method for producing silver or gold nanoparticles

---

EP3177142B1|2018-05-23|A process for preparing an antimicrobial particulate composition

---

US6939566B2|2005-09-06|Microbicidal formulations and methods to control microorganisms

---

US10016525B2|2018-07-10|Antimicrobial compositions for use in wound care products

---

CN102511503B|2014-07-02|Efficient and environmentally-friendly antibacterial and mildewproof inorganic composite nano-powder slurry and its preparation method

---

Jain et al.2005|Potential of silver nanoparticle‐coated polyurethane foam as an antibacterial water filter

---

US20120301528A1|2012-11-29|Compositions and methods for antimicrobial metal nanoparticles

同族专利:

---

公开号 | 公开日

---

引用文献:

---

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

---

法律状态:
2002-10-15|Application filed by 김인달

---

2002-10-15|Priority to KR1020020062657A

---

2004-04-28|Publication of KR20040033529A

优先权:

---

申请号 | 申请日 | 专利标题

---

KR1020020062657A|KR20040033529A|2002-10-15|2002-10-15|Process for producing antibiotic montmorillonite powder in which ag or cu or their oxides are combined with montmorillonite|